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single molecule array simoa srx platform  (Quanterix)


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    Structured Review

    Quanterix single molecule array simoa srx platform
    Single Molecule Array Simoa Srx Platform, supplied by Quanterix, used in various techniques. Bioz Stars score: 99/100, based on 680 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/sr+x+single+molecule+array/SR-X/pm42546452-76-20-26
    Average 99 stars, based on 680 article reviews
    single molecule array simoa srx platform - by Bioz Stars, 2026-10
    99/100 stars

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    other:

    Article Title: Temporal dynamics of white matter hyperintensities related to Alzheimer's disease in adults with Down syndrome.
    Article Snippet: AlejandraO.Morcillo-Nieto1,2,3 Mateus Rozalem-Aranha1,4 LuciaMaure-Blesa1,2,5 Íñigo Rodríguez-Baz1,2 José Enrique Arriola-Infante6 Maria Franquesa-Mullerat1,3 Sara E. Zsadanyi1,2,3 Lídia Vaqué-Alcázar1,7,8 José Allende Parra1,3 Zili Zhao1,3 Javier Arranz1,5 Laura Videla1,2,9 Isabel Barroeta1,2 Laura Del Hoyo Soriano1,2 Bessy Benejam1,9 Susana Fernández9 Aida SanjuanHernandez1 Lucia Pertierra10,1,2 Sandra Giménez1,2,11 Daniel Alcolea1,2 Olivia Belbin1,2 Alberto Lleó1,2 María Carmona-Iragui1,2,9 Juan Fortea1,2,9 Alexandre Bejanin1,2

    Clinical Proteomics:

    Article Title: Temporal dynamics of white matter hyperintensities related to Alzheimer's disease in adults with Down syndrome
    Article Snippet: We quantified Aβ peptide 1‐40 (Aβ 40 ), Aβ peptide 1‐42 (Aβ 42 ), and tau phosphorylated at threonine 181 (pTau181) in CSF using a commercially available immunoassay in a fully automated platform (Lumipulse; Fujirebio‐Europe), following a previously published protocol. .. Additionally, CSF and plasma glial fibrillary acidic protein (GFAP) concentrations were measured using the SR‐X single‐molecule array (Quanterix). .. CSF neurofilament light chain (NfL) and YKL‐40 (also known as chitinase 3‐like 1) levels were measured with commercially available enzyme‐linked immunosorbent assays (NF‐Light Assay, UmanDiagnostics, and MicroVue EIA, Quidel, respectively) according to the manufacturer's recommendations.



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    (A) Total protein concentrations in cerebrospinal fluid samples from healthy (n=5) controls and Parkinson’s disease (n=10) patients. (B) Total αSyn concentrations in the same CSF samples. (C) Tyr39-nitrated αSyn concentrations measured by SIMOA in CSF samples from healthy controls and Parkinson’s disease patients. Box-and-whisker plots show the median, upper and lower quartiles, and maximum and minimum values as whiskers. *** P < 0.001, unpaired t -test.

    Journal: bioRxiv

    Article Title: Antibody treatment targeting nitrated alpha-synuclein counteracts protein spreading pathology

    doi: 10.64898/2026.05.21.726933

    Figure Lengend Snippet: (A) Total protein concentrations in cerebrospinal fluid samples from healthy (n=5) controls and Parkinson’s disease (n=10) patients. (B) Total αSyn concentrations in the same CSF samples. (C) Tyr39-nitrated αSyn concentrations measured by SIMOA in CSF samples from healthy controls and Parkinson’s disease patients. Box-and-whisker plots show the median, upper and lower quartiles, and maximum and minimum values as whiskers. *** P < 0.001, unpaired t -test.

    Article Snippet: A single-molecule array (SIMOA) assay was developed on the Quanterix SR-X platform (Billerica, MA, USA) to quantify Tyr39-nitrated αSyn in human CSF.

    Techniques: Whisker Assay